Given my remarks above, the rule of thumb is to keep the fuel CG somewhere around the typical location of the aft pilothouse bulkhead. Other thoughts ... the ideal trim of a Great Alaskan at rest is the bow trimming higher than the stern by 1" to 2", definitely not down at the bow, when the boat has half fuel, most of the gear, and no people in it - self-draining when unattended at a dock (you can also add slope to the cockpit deck to help on this topic). You want water to drain aft in other words. The other side of the coin is that boats, like wives, tend to gain weight in the rear over time... fishermen, ice boxes, more gear than planned on etc. You don't want to trim too low at the stern on the first pass either. Before you worry too much about this stuff though ... don't. As I stated above, close is close enough and these boats are big enough to be forgiving of slightly non-optimal layouts (all boats are non-optimal in one way or another!)
Brian